CLIC3 antibody

Catalog No. ABIN499045

This Rabbit Polyclonal antibody specifically detects CLIC3 in WB. It exhibits reactivity toward Human.

Quick Overview for CLIC3 antibody (ABIN499045)

Target: CLIC3 (Chloride Intracellular Channel 3 (CLIC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLIC3 Antibody

Specificity: This antibody detects endogenous levels of CLIC3 protein. (region surrounding Phe56)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLIC3

Target: CLIC3 (Chloride Intracellular Channel 3 (CLIC3))

Alternative Name: CLIC3

Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.Synonyms: Chloride intracellular channel protein 3

Molecular Weight: approx. 27 kDa

Gene ID: 9022

NCBI Accession: NP_004660

UniProt: O95833