CLDN8 antibody

Catalog No. ABIN499047

The Rabbit Polyclonal anti-CLDN8 antibody (ABIN499047) specifically detects CLDN8 in WB. The antibody is reactive with Human samples.

Quick Overview for CLDN8 antibody (ABIN499047)

Target: CLDN8 (Claudin 8 (CLDN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLDN8 Antibody

Specificity: This antibody detects endogenous levels of Claudin-8 protein. (region surrounding Ile118)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Alternative Name: Claudin-8 / CLDN8

Background: Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-8 is a multi-pass membrane protein that belongs to the claudin family. Localized to the caput and the lateral margins of principal cells, claudin-8 plays an important role in tight junction-specific obliteration of the intercellular space.Synonyms: PRO1573, UNQ779

Molecular Weight: approx. 28 kDa

Gene ID: 9073

NCBI Accession: NP_955360

UniProt: P56748

Pathways: Hepatitis C