MRPS36 antibody

Catalog No. ABIN499092

Product Details anti-MRPS36 Antibody

Target: MRPS36 (Mitochondrial Ribosomal Protein S36 (MRPS36))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS36 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of MRP-S36 protein. (region surrounding Val36)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000. Immunohistocemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for MRPS36

Target: MRPS36 (Mitochondrial Ribosomal Protein S36 (MRPS36))

Alternative Name: MRPS36 (MRPS36 Products)

Synonyms: MRP-S36 antibody, 1110018B13Rik antibody, S36mt antibody, mitochondrial ribosomal protein S36 antibody, MRPS36 antibody, Mrps36 antibody

Background: Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S36 (mitochondrial ribosomal protein S36), is a 103 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-S36 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Synonyms: 28S ribosomal protein S36, DC47, S36mt, mitochondrial

Molecular Weight: approx. 15 kDa

Gene ID: 92259

NCBI Accession: NP_150597

UniProt: P82909