CD5L antibody (N-Term)

Catalog No. ABIN499247

The Rabbit Polyclonal anti-CD5L antibody has been validated for WB, IHC (p) and IF. It is suitable to detect CD5L in samples from Human and Mouse.

Quick Overview for CD5L antibody (N-Term) (ABIN499247)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD5L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-CD5L Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to AIM.

Purification: Affinity chromatography purified via peptide column

Immunogen: AIM antibody was raised against a 16 amino acid peptide near the amino terminus of human AIM.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: AIM antibody can be used for the detection of AIM at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L / API6

Background: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.Synonyms: AIM, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha

Gene ID: 922

UniProt: O43866