BANF1 antibody (N-Term)

Catalog No. ABIN499409

The Rabbit Polyclonal anti-BANF1 antibody has been validated for WB, IF and EIA. It is suitable to detect BANF1 in samples from Human, Mouse and Rat.

Quick Overview for BANF1 antibody (N-Term) (ABIN499409)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BANF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-BANF1 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to BANF1.

Purification: Affinity chromatography purified via peptide column

Immunogen: BANF1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human BANF1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: BANF1 antibody can be used for detection of BANF1 at 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1

Background: Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BAF also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BAF will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BAF is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.Synonyms: BAF, BCRG1, Barrier-to-autointegration factor, Breakpoint Cluster Region Protein 1

Gene ID: 8815

UniProt: O75531