alpha Fetoprotein antibody (AbBy Fluor® 750)

Catalog No. ABIN4996205

This anti-alpha Fetoprotein antibody is a Mouse Monoclonal antibody detecting alpha Fetoprotein in WB and IF (p). Suitable for Human and Rat.

Quick Overview for alpha Fetoprotein antibody (AbBy Fluor® 750) (ABIN4996205)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: A2

Product Details anti-alpha Fetoprotein Antibody (AbBy Fluor® 750)

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: Full length human AFP protein

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: AFP

Background:

Synonyms: AFPD, FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP

Background: Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Gene ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process