ANKRD26 antibody (AbBy Fluor® 680)

Catalog No. ABIN4996539

This Rabbit Polyclonal antibody specifically detects ANKRD26 in WB and IF (p). It exhibits reactivity toward Human.

Quick Overview for ANKRD26 antibody (AbBy Fluor® 680) (ABIN4996539)

Target: ANKRD26 (Ankyrin Repeat Domain 26 (ANKRD26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD26 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ANKRD26 Antibody (AbBy Fluor® 680)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD26

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKRD26

Target: ANKRD26 (Ankyrin Repeat Domain 26 (ANKRD26))

Alternative Name: ANKRD26

Background:

Synonyms: Ankrd26, Ankyrin repeat domain 26, Ankyrin repeat domain-containing protein 26, Ankyrin repeat domaincontaining protein 26, ANR26_HUMAN.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD26 (ankyrin repeat domain-containing protein 26) is a 1709 amino acid protein that contains five ANK repeats. Expressed at high level in many tissues, including brain, liver, kidney and heart, ANKRD26 may be phosphorylated upon DNA damage by Atm or ATR. ANKRD26 is also expressed in the arcuate and ventromedial nuclei within the hypothalamus and in the ependyma and the circumventricular organs that act as an interface between the peripheral circulation and the brain. It is suggested that alterations in the gene encoding ANKRD26 may lead to obesity. Three isoforms of ANKRD26 exists due to alternative splicing events.

Gene ID: 22852

Pathways: Feeding Behaviour