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CUEDC1 antibody (C-Term)

This anti-CUEDC1 antibody is a Rabbit Polyclonal antibody detecting CUEDC1 in WB, IHC (p) and EIA. Suitable for Human, Mouse and Rat.
Catalog No. ABIN499686

Quick Overview for CUEDC1 antibody (C-Term) (ABIN499686)

Target

See all CUEDC1 Antibodies
CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This CUEDC1 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    C-Term

    Specificity

    This antibody reacts to CUEDC1.

    Purification

    Affinity chromatography purified via peptide column

    Immunogen

    CUEDC1 antibody was raised against a 16 amino acid peptide near the carbocy terminus of human CUEDC1.

    Isotype

    IgG
  • Application Notes

    ELISA. Western Blot: CUEDC1 antibody can be used for detection of CUEDC1 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C.
  • Target

    CUEDC1 (CUE Domain Containing 1 (CUEDC1))

    Alternative Name

    CUEDC1

    Background

    The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. CUEDC1 antibody will not cross-react with CUEDC2.Synonyms: CUE domain-containing protein 1

    Gene ID

    404093

    UniProt

    Q9NWM3
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