BAIAP2 antibody (AA 151-250) (AbBy Fluor® 750)

Catalog No. ABIN4997180

This anti-BAIAP2 antibody is a Rabbit Polyclonal antibody detecting BAIAP2 in WB, IF (cc), IF (p). Suitable for Human, Mouse, Rat.

Quick Overview for BAIAP2 antibody (AA 151-250) (AbBy Fluor® 750) (ABIN4997180)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAIAP2 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-BAIAP2 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRS P53

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2

Background:

Synonyms: Insulin receptor substrate P53, IRSp53, IRS P53, IRS-P53, Baiap2, BAI1 associated protein 2 isoform 3, Brain-specic angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Insulin receptor tyrosine kinase substrate protein p53, Insulin receptor substrate p53, Insulin receptor substrate protein of 53 kDa, IRSp53, BAIP2_HUMAN, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, FLAF3, IRS-58, IRSp53/58.

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.

Gene ID: 10458