Biliverdin Reductase antibody (AA 161-260) (AbBy Fluor® 750)

Catalog No. ABIN4997501

This anti-Biliverdin Reductase antibody is a Rabbit Polyclonal antibody detecting Biliverdin Reductase in FACS, IF (cc) and IF (p). Suitable for Human and Rat.

Quick Overview for Biliverdin Reductase antibody (AA 161-260) (AbBy Fluor® 750) (ABIN4997501)

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Biliverdin Reductase antibody is conjugated to AbBy Fluor® 750

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Biliverdin Reductase Antibody (AbBy Fluor® 750)

Binding Specificity: AA 161-260

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BLVRA/Biliverdin Reductase

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Biliverdin Reductase

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Alternative Name: BLVRA/Biliverdin Reductase

Background:

Synonyms: Biliverdin IX alpha reductase, Biliverdin reductase A, BLVR A, BLVR, BLVRA, BVR A, BVR, BVRA, zinc-metalloprotein, BIEA_HUMAN.

Background: In human liver cytosolic fractions, four forms of biliverdin reductase have been identified, including two biliverdin-IX Beta reductases and two biliverdin-IX Alpha reductases, designated isozymes I and II and isozymes III and IV, respectively. Biliverdin reductase A (BLVRA), also designated biliverdin-IX Alpha-reductase, belongs to the GFO/iIDH/MocA family and the biliverdin reductase subfamily. The gene that encodes this cytoplasmic protein maps to chromosome 7p14-cen. BLVRA reduces biliverdin IX ?(the ?methene bridge of the open tetrapyrrole) to bilirubin with the concomitant oxidation of an NADH or NADPH cofactor (bilirubin + NADP+ = biliverdin + NADPH). BLVRA is expressed primarily in liver.

Gene ID: 644