FTO antibody (N-Term)

Catalog No. ABIN499863

The Rabbit Polyclonal anti-FTO antibody (ABIN499863) specifically detects FTO in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for FTO antibody (N-Term) (ABIN499863)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FTO Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to FTO.

Purification: Affinity chromatography purified via peptide column

Immunogen: FTO antibody was raised against a 15 amino acid peptide from near the amino terminus of human FTO.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Alternative Name: FTO

Background: Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.Synonyms: Fat mass and obesity-associated protein, KIAA1752

Gene ID: 79068

UniProt: Q9C0B1