C9ORF173 antibody (AbBy Fluor® 750)
Quick Overview for C9ORF173 antibody (AbBy Fluor® 750) (ABIN4998784)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Mouse
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Predicted Reactivity
- Human,Rat,Dog
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human C9orf173
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Isotype
- IgG
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Application Notes
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- C9ORF173 (Chromosome 9 Open Reading Frame 173 (C9ORF173))
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Alternative Name
- C9orf173
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Background
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Synonyms: C9orf173, Chromosome 9 open reading frame 173, CI173_HUMAN, Uncharacterized protein C9orf173.
Background: C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
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Gene ID
- 441476
Target
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