CCDC148 antibody (AA 401-500) (AbBy Fluor® 680)

Catalog No. ABIN4999218

This Rabbit Polyclonal antibody specifically detects CCDC148 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for CCDC148 antibody (AA 401-500) (AbBy Fluor® 680) (ABIN4999218)

Target: CCDC148 (Coiled-Coil Domain Containing 148 (CCDC148))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC148 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CCDC148 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 401-500

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC148

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC148

Target: CCDC148 (Coiled-Coil Domain Containing 148 (CCDC148))

Alternative Name: CCDC148

Background:

Synonyms: CCDC 148, coiled coil domain containing 148, coiled-coil domain containing 148, CC148_HUMAN.

Background: CCDC148 (coiled-coil domain containing 148), also known as MGC125590 or MGC125588, is a 591 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.