Interleukin 17a antibody (N-Term)

Catalog No. ABIN499978

This Rabbit Polyclonal antibody specifically detects Interleukin 17a in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Interleukin 17a antibody (N-Term) (ABIN499978)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Interleukin 17a Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to Il-17.

Purification: Affinity chromatography purified via peptide column

Immunogen: IL-17 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-17A.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: Interleukin-17A (IL17A)

Background: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17

Gene ID: 3605

NCBI Accession: NP_002181

UniProt: Q16552