CRTAC1 antibody (AA 301-400) (AbBy Fluor® 680)

Catalog No. ABIN5000574

This Rabbit Polyclonal antibody specifically detects CRTAC1 in WB and IF (p). It exhibits reactivity toward Human.

Quick Overview for CRTAC1 antibody (AA 301-400) (AbBy Fluor® 680) (ABIN5000574)

Target: CRTAC1 (Cartilage Acidic Protein 1 (CRTAC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAC1 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CRTAC1 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTAC1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CRTAC1

Target: CRTAC1 (Cartilage Acidic Protein 1 (CRTAC1))

Alternative Name: CRTAC1

Background:

Synonyms: 68 kDa chondrocyte expressed protein, 68 kDa chondrocyte-expressed protein, Acidic secreted protein in cartilage, ASPIC, ASPIC1, Cartilage acidic protein 1, Cartilage acidic protein 1 precursor, CEP 68, CEP-68, CEP68, CRAC1_HUMAN, CRTAC1, Protein CRTAC1-B, W307.

Background: CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome.

Gene ID: 55118