JMJD6 antibody (N-Term)

Catalog No. ABIN500088

This anti-JMJD6 antibody is a Rabbit Polyclonal antibody detecting JMJD6 in WB, IHC (p) and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for JMJD6 antibody (N-Term) (ABIN500088)

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-JMJD6 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects JMJD6.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: JMJD6 antibody was raised against a 15 amino acid peptide from near the amino terminus of human JMJD6.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for JMJD6

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: JMJD6 / PTDSR

Background: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing.Synonyms: Histone arginine demethylase JMJD6, JmjC domain-containing protein 6, Jumonji domain-containing protein 6, KIAA0585, Phosphatidylserine receptor

Gene ID: 23210

UniProt: Q6NYC1