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NKIRAS1 antibody (Center)

This Rabbit Polyclonal antibody specifically detects NKIRAS1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN500110

Quick Overview for NKIRAS1 antibody (Center) (ABIN500110)

Target

See all NKIRAS1 Antibodies
NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivity

  • 32
  • 25
  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 40
  • 7
Rabbit

Clonality

  • 40
  • 7
Polyclonal

Conjugate

  • 24
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NKIRAS1 antibody is un-conjugated

Application

  • 43
  • 23
  • 13
  • 13
  • 7
  • 6
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Specificity

    This antibody detects both kappaB-ras1 and kappaB-ras2.

    Cross-Reactivity (Details)

    Species reactivity (tested):Human, mouse, rat

    Purification

    Peptide afinity chromatography

    Immunogen

    KappaB ras antibody was raised against a 18 amino acid peptide from near the center of human KappaB ras 1.

    Isotype

    IgG
  • Application Notes

    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

    Alternative Name

    NKIRAS1

    Background

    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1

    Gene ID

    28512

    UniProt

    Q9NYS0
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