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NKIRAS1 antibody (N-Term)

NKIRAS1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN634451
  • Target See all NKIRAS1 Antibodies
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 42
    • 31
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 50
    • 7
    Rabbit
    Clonality
    • 50
    • 7
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKIRAS1 antibody is un-conjugated
    Application
    • 47
    • 27
    • 13
    • 13
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    NKIRAS1 antibody was raised against the N terminal of NKIRAS1
    Purification
    Affinity purified
    Immunogen
    NKIRAS1 antibody was raised using the N terminal of NKIRAS1 corresponding to a region with amino acids CETMEDVYMASVETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLV
    Top Product
    Discover our top product NKIRAS1 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    NKIRAS1 Blocking Peptide, catalog no. 33R-1680, is also available for use as a blocking control in assays to test for specificity of this NKIRAS1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NKIRAS1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Alternative Name
    NKIRAS1 (NKIRAS1 Products)
    Synonyms
    NKIRAS1 antibody, KBRAS1 antibody, kappaB-Ras1 antibody, zgc:92823 antibody, kbras1 antibody, 2400004O09Rik antibody, NFKB inhibitor interacting Ras like 1 antibody, NFKB inhibitor interacting Ras-like 1 antibody, NFKB inhibitor interacting Ras-like 1 S homeolog antibody, NFKB inhibitor interacting Ras-like protein 1 antibody, NKIRAS1 antibody, nkiras1 antibody, nkiras1.S antibody, Nkiras1 antibody
    Background
    NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
    Molecular Weight
    22 kDa (MW of target protein)
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