LRFN1 antibody (C-Term)

Catalog No. ABIN500186

The Rabbit Polyclonal anti-LRFN1 antibody is suitable to detect LRFN1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC (p) and EIA.

Quick Overview for LRFN1 antibody (C-Term) (ABIN500186)

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRFN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-LRFN1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects LRFN1. It is predicted to not cross-react with other members of the LRFN family.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: LRFN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRFN1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for LRFN1

Target: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Alternative Name: LRFN1

Background: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.Synonyms: KIAA1484, Leucine-rich repeat and fibronectin type III domain-containing protein 1, SALM2, Synaptic adhesion-like molecule 2

Gene ID: 57622

UniProt: Q9P244

Pathways: Synaptic Membrane