FAM101A antibody (AA 111-216) (AbBy Fluor® 750)

Catalog No. ABIN5002346

The AbBy Fluor® 750-conjugated Rabbit Polyclonal anti-FAM101A antibody (ABIN5002346) specifically detects FAM101A in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for FAM101A antibody (AA 111-216) (AbBy Fluor® 750) (ABIN5002346)

Target: FAM101A (Family with Sequence Similarity 101, Member A (FAM101A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM101A antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FAM101A Antibody (AbBy Fluor® 750)

Binding Specificity: AA 111-216

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM101A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM101A

Target: FAM101A (Family with Sequence Similarity 101, Member A (FAM101A))

Alternative Name: FAM101A

Background:

Synonyms: cfm, 3110032G18Rik, cfm2, F101A_HUMAN, FAM101A, Family with sequence similarity 101, member A, FLJ44614, Hypothetical protein LOC73121, Protein FAM101A.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM101A gene product has been provisionally designated FAM101A pending further characterization.

Gene ID: 144347