MATN2 antibody (C-Term)
Quick Overview for MATN2 antibody (C-Term) (ABIN500242)
Target
See all MATN2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- C-Term
-
Specificity
- This antibody detects Matrilin-2.
-
Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
-
Purification
- Peptide affinity chromatography
-
Immunogen
- MATN2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human MATN2.
-
Isotype
- IgG
-
-
-
-
Application Notes
-
ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS containing 0.02 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- MATN2 (Matrilin 2 (MATN2))
-
Alternative Name
- Matrilin-2
-
Background
- Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.Synonyms: MATN2
-
Gene ID
- 4147
-
NCBI Accession
- NP_085072
-
UniProt
- O00339
Target
-