MTCH2 antibody (N-Term)

Catalog No. ABIN500296

This Rabbit Polyclonal antibody specifically detects MTCH2 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for MTCH2 antibody (N-Term) (ABIN500296)

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTCH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MTCH2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects MTCH2.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogen: MTCH2 antibody was raised against a 15 amino acid peptide near the amino terminus of human MTCH2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochgemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for MTCH2

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Alternative Name: MTCH2

Background: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.Synonyms: HSPC032, MIMP, Met-induced mitochondrial protein, Mitochondrial carrier homolog 2

Gene ID: 56428

UniProt: Q791V5