GBAS antibody (AA 21-120) (AbBy Fluor® 680)

Catalog No. ABIN5003253

This Rabbit Polyclonal antibody specifically detects GBAS in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for GBAS antibody (AA 21-120) (AbBy Fluor® 680) (ABIN5003253)

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBAS antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GBAS Antibody (AbBy Fluor® 680)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBAS

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Alternative Name: GBAS

Background:

Synonyms: 4 nitrophenylphosphatase domain and non neuronal SNAP25 like 2, gbas, Glioblastoma amplied sequence, Glioblastoma-amplied sequence, NIPS2_HUMAN, Nipsnap homolog 2, NipSnap2, Protein NipSnap homolog 2.

Background: NIPSNAP2 is a 286 amino acid protein that is abundantly expressed in heart and skeletal muscle. Belonging to the NIPSNAP family, NIPSNAP2 may be involved in vesicular transport. NIPSNAP2 contains a signal peptide, a transmembrane domain and two tyrosine phosphorylation sites. NIPSNAP2 is encoded by a gene mapping to human chromosome 7p11.2. Chromosomal region 7p12 is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor. Human chromosome 7 houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Gene ID: 2631

Pathways: Ribonucleoside Biosynthetic Process