F11R antibody (AA 40-70) (AbBy Fluor® 750)

Catalog No. ABIN5005654

The Rabbit Polyclonal anti-F11R antibody has been validated for WB. It is suitable to detect F11R in samples from Human, Mouse and Rat.

Quick Overview for F11R antibody (AA 40-70) (AbBy Fluor® 750) (ABIN5005654)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB)

Product Details anti-F11R Antibody (AbBy Fluor® 750)

Binding Specificity: AA 40-70

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: JAM1

Background:

Synonyms: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1, Junctional adhesion molecule A, JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, F11R, UNQ264/PRO301

Background: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization