KLHL3 antibody (AA 51-160) (AbBy Fluor® 750)

Catalog No. ABIN5005927

The Rabbit Polyclonal anti-KLHL3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect KLHL3 in samples from Human.

Quick Overview for KLHL3 antibody (AA 51-160) (AbBy Fluor® 750) (ABIN5005927)

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL3 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KLHL3 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 51-160

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KLHL3

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Alternative Name: KLHL3

Background:

Synonyms: KLHL 3, FLJ40871, kelch Drosophila like 3, kelch like 3 Drosophila, kelch like 3, Kelch like protein 3, KIAA1129, MGC44594, KLHL3_HUMAN.

Background: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Gene ID: 26249