MATK antibody (AA 411-507) (AbBy Fluor® 750)

Catalog No. ABIN5006586

This Rabbit Polyclonal antibody specifically detects MATK in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for MATK antibody (AA 411-507) (AbBy Fluor® 750) (ABIN5006586)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATK antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MATK Antibody (AbBy Fluor® 750)

Binding Specificity: AA 411-507

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MATK

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Alternative Name: MATK

Background:

Synonyms: CHK, Csk homologous kinase, Csk type protein tyrosine kinase, CTK, Hematopoietic consensus tyrosine lacking kinase, HHYLTK, Hydroxyaryl protein kinase, HYL, HYL tyrosine kinase, HYLTK, Leukocyte carboxyl terminal src kinase related, Lsk, Megakaryocyte associated tyrosine kinase, Megakaryocyte associated tyrosine protein kinase, Protein kinase HYL, Tyrosine kinase MATK, Tyrosine protein kinase CTK, Tyrosylprotein kinase, MATK_HUMAN.

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Gene ID: 4145