MPZL2 antibody (AA 61-160) (AbBy Fluor® 680)

Catalog No. ABIN5007004

The Rabbit Polyclonal anti-MPZL2 antibody has been validated for WB, IF (cc), IF (p). It is suitable to detect MPZL2 in samples from Human.

Quick Overview for MPZL2 antibody (AA 61-160) (AbBy Fluor® 680) (ABIN5007004)

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL2 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MPZL2 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 61-160

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MPZL2/EVA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MPZL2

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Alternative Name: MPZL2/EVA1

Background:

Synonyms: Epithelial V like antigen 1, epithelial V-like antigen, EVA, EVA1, MPZL2, MPZL2 myelin protein zero like 2, myelin protein zero-like 2, Myelin protein zero like protein 2, MPZL2_HUMAN.

Background: Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].