PPP1R8 antibody (AA 21-120) (AbBy Fluor® 680)

Catalog No. ABIN5007653

This anti-PPP1R8 antibody is a Rabbit Polyclonal antibody detecting PPP1R8 in WB, IF (cc) and IF (p). Suitable for Mouse and Zebrafish (Danio rerio).

Quick Overview for PPP1R8 antibody (AA 21-120) (AbBy Fluor® 680) (ABIN5007653)

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Reactivity: Mouse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R8 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PPP1R8 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse, Zebrafish (Danio rerio)

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIPP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PPP1R8

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Alternative Name: NIPP1/ ARD1

Background:

Synonyms: Activator of RNA decay, ARD 1, ARD1, Homolog of E.coli RNase E, NIPP 1, NIPP1, Nuclear inhibitor of protein phosphatase 1, Nuclear subunit of PP1, PPP1R8, Protein phosphatase 1 regulatory inhibitor subunit 8, Protein phosphatase 1 regulatory subunit 8, RNase E.

Background: Inhibitor subunit of the major nuclear protein phosphatase 1 (PP1). It has RNA binding activity but does not cleave RNA and may target PP1 to RNA associated substrates. May also be involved in pre mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.

Gene ID: 5511