NOG antibody (AA 28-130) (AbBy Fluor® 750)

Catalog No. ABIN5007763

The Rabbit Polyclonal anti-NOG antibody has been validated for WB, FACS, IF (cc) and IF (p). It is suitable to detect NOG in samples from Mouse and Rat.

Quick Overview for NOG antibody (AA 28-130) (AbBy Fluor® 750) (ABIN5007763)

Target: NOG (Noggin (NOG))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NOG Antibody (AbBy Fluor® 750)

Binding Specificity: AA 28-130

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Noggin

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: Noggin

Background:

Synonyms: NOG, NOGG_HUMAN, Noggin, SYM 1, SYM1, Symphalangism 1 proximal, Synostoses multiple syndrome 1, SYNS 1, SYNS1.

Background: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 (PubMed:21976273).

Gene ID: 9241

UniProt: Q13253

Pathways: Stem Cell Maintenance, Tube Formation