PSMA4 antibody (AA 161-261) (AbBy Fluor® 680)

Catalog No. ABIN5009340

This Rabbit Polyclonal antibody specifically detects PSMA4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for PSMA4 antibody (AA 161-261) (AbBy Fluor® 680) (ABIN5009340)

Target: PSMA4 (Proteasome Subunit alpha 4 (PSMA4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA4 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PSMA4 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 161-261

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Horse,Monkey

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSMA4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PSMA4

Target: PSMA4 (Proteasome Subunit alpha 4 (PSMA4))

Alternative Name: PSMA4

Background:

Synonyms: HC9, HsT17706, Macropain subunit C9, MGC111191, MGC12467, MGC24813, Multicatalytic endopeptidase complex subunit C9, Proteasome prosome macropain subunit alpha type 4, Proteasome alpha 4 subunit, Proteasome component C9, Proteasome subunit alpha type 4, Proteasome subunit alpha type-4, Proteasome subunit HC9, Proteasome subunit L, PSA4_HUMAN, PSC9, PSMA 4, psmA4.

Background: The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on the organism. All of the subunits fall into one of two types: alpha subunits, which are structural, serve as docking domains for the regulatory particles and exterior gates blocking unregulated access to the interior cavity, or beta subunits, which are predominantly catalytic. The outer two rings in the proteasome consist of seven ?subunits each, and the inner two rings each consist of seven beta subunits.

Gene ID: 5685

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA