RASSF8 antibody (AA 101-200) (AbBy Fluor® 750)

Catalog No. ABIN5009635

The Rabbit Polyclonal anti-RASSF8 antibody is suitable to detect RASSF8 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for RASSF8 antibody (AA 101-200) (AbBy Fluor® 750) (ABIN5009635)

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF8 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RASSF8 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RASSF8

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RASSF8

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Alternative Name: RASSF8

Background:

Synonyms: HOJ1, C12orf2, Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1, RASSF8

Background: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12,22)(p11.2,q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID: 11228

UniProt: Q8NHQ8

Pathways: Chromatin Binding