RNF19B antibody (AbBy Fluor® 750)

Catalog No. ABIN5009954

This anti-RNF19B antibody is a Rabbit Polyclonal antibody detecting RNF19B in WB and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for RNF19B antibody (AbBy Fluor® 750) (ABIN5009954)

Target: RNF19B (Ring Finger Protein 19B (RNF19B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF19B antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RNF19B Antibody (AbBy Fluor® 750)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF19B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF19B

Target: RNF19B (Ring Finger Protein 19B (RNF19B))

Alternative Name: RNF19B

Background:

Synonyms: E3 ubiquitin-protein ligase RNF19B, IBR domain containing 3, IBR domain-containing protein 3, IBRDC3, Natural killer lytic-associated molecule, NKLAM, RING finger protein 19B, RN19B_HUMAN, rnf19b.

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Gene ID: 127544