CNTN2 antibody (AA 161-260) (AbBy Fluor® 750)
Quick Overview for CNTN2 antibody (AA 161-260) (AbBy Fluor® 750) (ABIN5011322)
Target
See all CNTN2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 161-260
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Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human TAG1
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Isotype
- IgG
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- CNTN2 (Contactin 2 (Axonal) (CNTN2))
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Alternative Name
- TAG1
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Background
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Synonyms: Axonal glycoprotein TAG 1, Axonal glycoprotein TAG-1, Axonal glycoprotein TAG1, Axonin 1, Axonin-1, Axonin1, AXT, CNTN 2, Cntn2, CNTN2_HUMAN, contactin 2 axonal, Contactin 2, Contactin-2, Contactin2, DKFZp781D102, MGC157722, TAG 1, TAG 564, TAG564, TAX 1, TAX, TAX-1, TAX1, Transient axonal glycoprotein 1, Transiently expressed axonal glycoprotein.
Background: Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
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Gene ID
- 6900
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
Target
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