USP22 antibody (AA 121-220) (AbBy Fluor® 750)

Catalog No. ABIN5012280

This Rabbit Polyclonal antibody specifically detects USP22 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Rat and Xenopus laevis.

Quick Overview for USP22 antibody (AA 121-220) (AbBy Fluor® 750) (ABIN5012280)

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Reactivity: Human, Rat, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP22 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-USP22 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 121-220

Cross-Reactivity: Human, Rat, Xenopus laevis

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human USP22

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for USP22

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Alternative Name: USP22

Background:

Synonyms: USP3L, Ubiquitin carboxyl-terminal hydrolase 22, Deubiquitinating enzyme 22, Ubiquitin thioesterase 22, Ubiquitin-specific-processing protease 22, USP22, KIAA1063

Background: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Gene ID: 23326

UniProt: Q9UPT9