USP3 antibody (AA 31-130) (AbBy Fluor® 750)

Catalog No. ABIN5012284

The Rabbit Polyclonal anti-USP3 antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect USP3 in samples from Human.

Quick Overview for USP3 antibody (AA 31-130) (AbBy Fluor® 750) (ABIN5012284)

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP3 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-USP3 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 31-130

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human USP3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for USP3

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Alternative Name: USP3

Background:

Synonyms: Deubiquitinating enzyme 3, EC 3.1.2.15, SIH003, Ubiquitin carboxyl-terminal hydrolase 3, Ubiquitin specic peptidase 3, Ubiquitin specic processing protease 3, Ubiquitin Specic Protease 3, Ubiquitin thioesterase 3, Ubiquitin thiolesterase 3, Ubiquitin-specic-processing protease 3, UBP, UBP3_HUMAN, Usp3, USP-3, USP 3.

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP3 (ubiquitin specific peptidase 3), also known as UBP or SIH003, is a 520 amino acid protein that contains one UBP-type zinc finger and belongs to the peptidase C19 family. Expressed ubiquitously with highest levels present in pancreas, USP3 catalyzes the conversion of a ubiquitin C-terminal thioester to a free ubiquitin and a thiol. The gene encoding USP3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.

Gene ID: 9960