GPR77
Reactivity: Human
FACS
Host: Rabbit
Chimeric
unconjugated
Fc fragment
Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target
GPR77
(G Protein-Coupled Receptor 77 (GPR77))
Alternative Name
C5L2/GPCR77
Background
C5a anaphylatoxin chemotactic receptor 2 (C5L2) encodes a G-protein coupled receptor 1, also known as C5L2, G protein-coupled receptor 77. C5L2 involved in the complement system of the innate immune response. It has high affinity and several receptors not only for C5a, desarginated C5a, and C3a, but also for desarginated C3a, the acylation-stimulating protein. Diseases associated with C5AR2 include artery diseases and sepsis. C5L2 expressed mainly on frontal cortex, hippocampus, hypothalamus, pons and liver.