HOXA9 antibody (AA 63-272)

Catalog No. ABIN5027256

This Rabbit Polyclonal antibody specifically detects HOXA9 in WB. It exhibits reactivity toward Human.

Quick Overview for HOXA9 antibody (AA 63-272) (ABIN5027256)

Target: HOXA9 (Homeobox A9 (HOXA9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXA9 Antibody

Binding Specificity: AA 63-272

Purification: Protein A Chromatography

Immunogen: A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for HOXA9

Target: HOXA9 (Homeobox A9 (HOXA9))

Alternative Name: HOXA9

Background: HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.

Molecular Weight: 30 kDa

Gene ID: 3205

UniProt: P31269