KAT5 antibody (AA 300-500)

Catalog No. ABIN5027563

The Rabbit Polyclonal anti-KAT5 antibody has been validated for WB. It is suitable to detect KAT5 in samples from Human.

Quick Overview for KAT5 antibody (AA 300-500) (ABIN5027563)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KAT5 Antibody

Binding Specificity: AA 300-500

Purification: Protein A Chromatography

Immunogen: A partial length recombinant TIP60 protein (amino acids 300-500) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: TIP60

Background: TIP60 (60 kDa Tat-interactive protein) alternatively called as Lysine acetyltransferase 5 (KAT5) or Histone acetyltransferase KAT5 is a member of MYST protein family with four isoforms (58, 53, 61 and 56 kDa). TIP60 plays important roles in regulating chromatin remodeling, transcription, DNA repair and apoptosis. TIP60 causes transcription activation by acetylating nucleosomal histones H4 and H2A. Mutations at gene level are associated with diseases like HIV-1, and Kaposis sarcoma. TIP60 is mainly expressed in brain tissue.

Molecular Weight: 55 kDa

Gene ID: 10524

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway