TLR1 antibody (AA 300-500)

Catalog No. ABIN5027567

This anti-TLR1 antibody is a Rabbit Polyclonal antibody detecting TLR1 in WB. Suitable for Human.

Quick Overview for TLR1 antibody (AA 300-500) (ABIN5027567)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLR1 Antibody

Binding Specificity: AA 300-500

Cross-Reactivity: Mouse (Murine)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 4-6 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Alternative Name: TLR1

Background: Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.

Molecular Weight: 110 kDa

Gene ID: 7096

UniProt: Q15399

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades