Villin 1 antibody (AA 108-322)

Catalog No. ABIN5027631

This Mouse Monoclonal antibody specifically detects Villin 1 in IHC and WB. It exhibits reactivity toward Human.

Quick Overview for Villin 1 antibody (AA 108-322) (ABIN5027631)

Target: Villin 1 (VIL1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Villin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: ABM4E64

Product Details anti-Villin 1 Antibody

Binding Specificity: AA 108-322

Purification: Protein G Chromatography

Immunogen: A partial length recombinant Villin protein (amino acids 108-322) was used as the immunogen for this antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 0.5 μg/mL, IHC-5-10 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for Villin 1

Target: Villin 1 (VIL1)

Alternative Name: Villin

Background: Villin is a protein that belongs to the gelsolin family of calcium-regulated actin-binding proteins. It is expressed in differentiated epithelial cells with a brush border such as intestinal villi, proximal renal tubules, oviduct, and seminiferous ducts. Villin shares structural and functional homology with two conserved families of proteins. One family of proteins, which includes gelsolin and adseverin, shares the conserved domain(s) found in the villin core. Villin regulates cell migration, cell death, and epithelial-to-mesenchymal transition underscoring the significance of this protein to epithelial cell function.

Molecular Weight: 90 kDa

Gene ID: 396423

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization