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Fibrillarin/Nop1p Nucleolar Marker antibody

The Mouse Monoclonal anti-Fibrillarin/Nop1p Nucleolar Marker antibody (ABIN504711) specifically detects Fibrillarin/Nop1p Nucleolar Marker in IF and WB. The antibody is reactive with Human, Mouse and Rat samples.
Catalog No. ABIN504711
$357.50
Plus shipping costs $50.00
0.5 mL
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for Fibrillarin/Nop1p Nucleolar Marker antibody (ABIN504711)

Target

Fibrillarin/Nop1p Nucleolar Marker

Reactivity

Human, Mouse, Rat

Host

Mouse

Clonality

Monoclonal

Application

Immunofluorescence (IF), Western Blotting (WB)
  • Cross-Reactivity

    Caenorhabditis elegans (C. elegans), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine)

    Purification

    Purified

    Immunogen

    Mice were injected with yeast nuclear preparations and hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates.

    Isotype

    IgG
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Storage

    -20 °C
  • Target

    Fibrillarin/Nop1p Nucleolar Marker

    Background

    The Nop1p protein is 327 amino acids in size (34. 5 kDa), is essential for yeast viability, and is localized in the nucleoli (1). The systematic name for S. cerevisiae Nop1 is YDL014W, and it is now known to be part of the small subunit processome complex, involved in the processing of pre-18S ribosomal RNA. Nop1p is the yeast homologue of a protein apparently found in all eukaryotes and archea generally called fibrillarin. Fibrillarin/Nop1p is extraordinarily conserved, so that the yeast and human proteins are 67% identical, and the human protein can functionally replace the yeast protein.
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