This Rabbit Polyclonal antibody specifically detects Macrophage Scavenger Receptor 1 in WB, IHC and ICC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow and Protozoa.
Optimal working dilutions should be determined experimentally by the investigator.
Restrictions
For Research Use only
Format
Liquid
Storage
-20 °C
Target
Macrophage Scavenger Receptor 1 (MSR1)
Background
Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).