OLIG2 antibody

Catalog No. ABIN504733

This Rabbit Polyclonal antibody specifically detects OLIG2 in WB, IHC, IP and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OLIG2 antibody (ABIN504733)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLIG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-OLIG2 Antibody

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Aff - Purified

Immunogen: Recombinant mouse Olig2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Alternative Name: Olig2

Background: Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development andmaturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord. Olig1 and 2are also a markers for the most common primary tumors of the human brain are thought to be of glial cell origin. Therefore, there is diagnostic potential of Olig markers to augment identification of oligodendroglial tumors.