AKR1B1 antibody (AA 1-316)

Catalog No. ABIN513260

The Mouse Polyclonal anti-AKR1B1 antibody has been validated for WB. It is suitable to detect AKR1B1 in samples from Human. There is 1 publication available.

Quick Overview for AKR1B1 antibody (AA 1-316) (ABIN513260)

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This AKR1B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKR1B1 Antibody

Binding Specificity: AA 1-316

Purpose: Mouse polyclonal antibody raised against a full-length human AKR1B1 protein.

Sequence: MASRLLLNNG AKMPILGLGT WKSPPGQVTE AVKVAIDVGY RHIDCAHVYQ NENEVGVAIQ EKLREQVVKR EELFIVSKLW CTYHEKGLVK GACQKTLSDL KLDYLDLYLI HWPTGFKPGK EFFPLDESGN VVPSDTNILD TWAAMEELVD EGLVKAIGIS NFNHLQVEMI LNKPGLKYKP AVNQIECHPY LTQEKLIQYC QSKGIVVTAY SPLGSPDRPW AKPEDPSLLE DPRIKAIAAK HNKTTAQVLI RFPMQRNLVV IPKSVTPERI AENFKVFDFE LSSQDMTTLL SYNRNWRVCA LLSCTSHKDY PFHEEF

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: AKR1B1 (AAH00260, 1 a.a. ~ 316 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1B1 antibody (ABIN513260)

Hernández-Ochoa, Robison, Contreras, Shen, Zhao, Schneider: "Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle." in: Experimental biology and medicine (Maywood, N.J.), Vol. 237, Issue 9, pp. 1068-83, (2012) (PubMed).

Target Details for AKR1B1

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Alternative Name: AKR1B1

Background: Full Gene Name: aldo-keto reductase family 1, member B1 (aldose reductase)
Synonyms: ADR,ALDR1,ALR2,AR,MGC1804

Gene ID: 231

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process