BST2 antibody (AA 1-180)

Catalog No. ABIN513823

This Mouse Monoclonal antibody specifically detects BST2 in WB, ELISA, IF and IP. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for BST2 antibody (AA 1-180) (ABIN513823)

Target: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 2E6

Product Details anti-BST2 Antibody

Binding Specificity: AA 1-180

Purpose: Mouse monoclonal antibody raised against a full-length recombinant BST2.

Sequence: MASTSYDYCR VPMEDGDKRC KLLLGIGILV LLIIVILGVP LIIFTIKANS EACRDGLRAV MECRNVTHLL QQELTEAQKG FQDVEAQAAT CNHTVMALMA SLDAEKAQGQ KKVEELEGEI TTLNHKLQDA SAEVERLRRE NQVLSVRIAD KKYYPSSQDS SSAAAPQLLI VLLGLSALLQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BST2 (AAH33873.1, 1 a.a. ~ 180 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-BST2 antibody (ABIN513823)

Lv, Wang, Zhang, Zhang, Wang, Zhu, Zuo, Liu, Li, Wu, Zhang, Yu, Wu, Zhao, Kong, Yu: "Epitope tags beside the N-terminal cytoplasmic tail of human BST-2 alter its intracellular trafficking and HIV-1 restriction." in: PLoS ONE, Vol. 9, Issue 10, pp. e111422, (2014) (PubMed).

Lv, Zhu, Wang, Zhang, Wang, Zuo, Liu, Zhang, Wu, Kong, Yu: "Purification of eukaryotic tetherin/Vpu proteins and detection of their interaction by ELISA." in: Protein expression and purification, Vol. 91, Issue 2, pp. 112-8, (2013) (PubMed).

Lv, Wang, Wang, Zuo, Zhu, Kong, Yu: "Polarity changes in the transmembrane domain core of HIV-1 Vpu inhibits its anti-tetherin activity." in: PLoS ONE, Vol. 6, Issue 6, pp. e20890, (2011) (PubMed).

Target Details for BST2

Target: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Alternative Name: BST2

Background: Full Gene Name: bone marrow stromal cell antigen 2
Synonyms: CD317

Gene ID: 684

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response