CIDEA antibody (AA 1-253)

Catalog No. ABIN514417

This Mouse Monoclonal antibody specifically detects CIDEA in WB, ELISA and IP. It exhibits reactivity toward Human and has been mentioned in 4+ publications.

Quick Overview for CIDEA antibody (AA 1-253) (ABIN514417)

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CIDEA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: 4B9

Product Details anti-CIDEA Antibody

Binding Specificity: AA 1-253

Purpose: Mouse monoclonal antibody raised against a full length recombinant CIDEA.

Sequence: MRGDRASGGP GNHNGSWARE GPRLGPSWKR GLWSPRGGPN RPAEPSRPLT FMGSQTKRVL FTPLMHPARP FRVSNHDRSS RRGVMASSLQ ELISKTLDAL VIATGLVTLV LEEDGTVVDT EEFFQTLGDN THFMILEKGQ KWMPGSQHVP TCSPPKRSGI ARVTFDLYRL NPKDFIGCLN VKATMYEMYS VSYDIRCTGL KGLLRSLLRF LSYSAQVTGQ FLIYLGTYML RVLDDKEERP SLRSQAKGRF TCG

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CIDEA (AAH31896, 1 a.a. ~ 253 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CIDEA antibody (ABIN514417)

Wang-Johanning, Rycaj, Plummer, Li, Yin, Frerich, Garza, Shen, Lin, Yan, Glynn, Dorsey, Hunt, Ambs, Johanning: "Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors." in: Journal of the National Cancer Institute, Vol. 104, Issue 3, pp. 189-210, (2012) (PubMed).

Ito, Nagasawa, Omae, Ide, Akasaka, Murakami: "Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes." in: Journal of lipid research, Vol. 52, Issue 8, pp. 1450-60, (2011) (PubMed).

Ito, Nagasawa, Hara, Ide, Murakami: "Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1676-84, (2010) (PubMed).

Puri, Ranjit, Konda, Nicoloro, Straubhaar, Chawla, Chouinard, Lin, Burkart, Corvera, Perugini, Czech: "Cidea is associated with lipid droplets and insulin sensitivity in humans." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 22, pp. 7833-8, (2008) (PubMed).

Target Details for CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Alternative Name: CIDEA

Background: Full Gene Name: cell death-inducing DFFA-like effector a
Synonyms: CIDE-A

Gene ID: 1149