CTLA4 antibody (AA 36-135)

Catalog No. ABIN514751

The Mouse Monoclonal anti-CTLA4 antibody has been validated for WB, ELISA and IF. It is suitable to detect CTLA4 in samples from Human. There is 1 publication available.

Quick Overview for CTLA4 antibody (AA 36-135) (ABIN514751)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTLA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2F1

Product Details anti-CTLA4 Antibody

Binding Specificity: AA 36-135

Purpose: Mouse monoclonal antibody raised against a partial recombinant CTLA4.

Sequence: KAMHVAQPAV VLASSRGIAS FVCEYASPGK ATEVRVTVLR QADSQVTEVC AATYMMGNEL TFLDDSICTG TSSGNQVNLT IQGLRAMDTG LYICKVELMY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CTLA4 (NP_005205, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CTLA4 antibody (ABIN514751)

Meletta, Müller Herde, Dennler, Fischer, Schibli, Krämer: "Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis." in: EJNMMI research, Vol. 6, Issue 1, pp. 1, (2016) (PubMed).

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA4

Background: Full Gene Name: cytotoxic T-lymphocyte-associated protein 4
Synonyms: CD152,CELIAC3,CTLA-4,GSE,IDDM12

Gene ID: 1493

NCBI Accession: NM_005214

Pathways: Cancer Immune Checkpoints