CTNS antibody (AA 1-400)

Catalog No. ABIN514757

The Rabbit Polyclonal anti-CTNS antibody has been validated for WB. It is suitable to detect CTNS in samples from Human. There is 1 publication available.

Quick Overview for CTNS antibody (AA 1-400) (ABIN514757)

Target: CTNS (Cystinosis, Nephropathic (CTNS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CTNS Antibody

Binding Specificity: AA 1-400

Purpose: Rabbit polyclonal antibody raised against a full-length human CTNS protein.

Sequence: MIRNWLTIFI LFPLKLVEKC ESSVSLTVPP VVKLENGSST NVSLTLRPPL NATLVITFEI TFRSKNITIL ELPDEVVVPP GVTNSSFQVT SQNVGQLTVY LHGNHSNQTG PRIRFLVIRS SAISIINQVI GWIYFVAWSI SFYPQVIMNW RRKSVIGLSF DFVALNLTGF VAYSVFNIGL LWVPYIKEQF LLKYPNGVNP VNSNDVFFSL HAVVLTLIII VQCCLYERGG QRVSWPAIGF LVLAWLFAFV TMIVAAVGVI TWLQFLFCFS YIKLAVTLVK YFPQAYMNFY YKSTEGWSIG NVLLDFTGGS FSLLQMFLQS YNNDQWTLIF GDPTKFGLGV FSIVFDVVFF IQHFCLYRKR PGLQAARTGS GSRLRQDWAP SLQPKALPQT TSVSASSLKG

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: CTNS (AAH32850.1, 1 a.a. ~ 400 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CTNS antibody (ABIN514757)

Sumayao, McEvoy, Martin-Martin, McMorrow, Newsholme: "Cystine dimethylester loading promotes oxidative stress and a reduction in ATP independent of lysosomal cystine accumulation in a human proximal tubular epithelial cell line." in: Experimental physiology, Vol. 98, Issue 10, pp. 1505-17, (2013) (PubMed).

Target Details for CTNS

Target: CTNS (Cystinosis, Nephropathic (CTNS))

Alternative Name: CTNS

Background: Full Gene Name: cystinosis, nephropathic
Synonyms: CTNS-LSB,PQLC4

Gene ID: 1497

NCBI Accession: NM_001031681