Cathepsin K antibody (AA 220-329)

Catalog No. ABIN514786

This Mouse Monoclonal antibody specifically detects Cathepsin K in WB, ELISA and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Cathepsin K antibody (AA 220-329) (ABIN514786)

Target: Cathepsin K (CTSK)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2F1

Product Details anti-Cathepsin K Antibody

Binding Specificity: AA 220-329

Purpose: Mouse monoclonal antibody raised against a partial recombinant CTSK.

Sequence: KCRGYREIPE GNEKALKRAV ARVGPVSVAI DASLTSFQFY SKGVYYDESC NSDNLNHAVL AVGYGIQKGN KHWIIKNSWG ENWGNKGYIL MARNKNNACG IANLASFPKM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CTSK (AAH16058, 220 a.a. ~ 329 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Cathepsin K antibody (ABIN514786)

Cordes, Bartling, Simm, Afar, Lautenschläger, Hansen, Silber, Burdach, Hofmann: "Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival." in: Lung cancer (Amsterdam, Netherlands), Vol. 64, Issue 1, pp. 79-85, (2009) (PubMed).

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: CTSK

Background: Full Gene Name: cathepsin K
Synonyms: CTS02,CTSO,CTSO1,CTSO2,MGC23107,PKND,PYCD

Gene ID: 1513

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades