CYP24A1 antibody (AA 415-514)

Catalog No. ABIN514852

This Mouse Monoclonal antibody specifically detects CYP24A1 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CYP24A1 antibody (AA 415-514) (ABIN514852)

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP24A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1E1

Product Details anti-CYP24A1 Antibody

Binding Specificity: AA 415-514

Purpose: Mouse monoclonal antibody raised against a partial recombinant CYP24A1.

Sequence: LMLNTQVLGS SEDNFEDSSQ FRPERWLQEK EKINPFAHLP FGVGKRMCIG RRLAELQLHL ALCWIVRKYD IQATDNEPVE MLHSGTLVPS RELPIAFCQR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYP24A1 (NP_000773, 415 a.a. ~ 514 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYP24A1 antibody (ABIN514852)

Helvig, Cuerrier, Hosfield, Ireland, Kharebov, Kim, Ramjit, Ryder, Tabash, Herzenberg, Epps, Petkovich: "Dysregulation of renal vitamin D metabolism in the uremic rat." in: Kidney international, Vol. 78, Issue 5, pp. 463-72, (2010) (PubMed).

Target Details for CYP24A1

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Alternative Name: CYP24A1

Background: Full Gene Name: cytochrome P450, family 24, subfamily A, polypeptide 1
Synonyms: CP24,CYP24,MGC126273,MGC126274,P450-CC24

Gene ID: 1591

NCBI Accession: NM_000782

Pathways: Metabolism of Steroid Hormones and Vitamin D